Delta will be operating to 35 destinations throughout the region.
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  • With resumption of service to Argentina, Chile and Ecuador, Delta is now operating to 35 destinations throughout the region.
  • Safety initiatives and booking flexibility in domestic and international markets make Delta the best choice for travel.
  • Extensive network enables the transport of essential goods and services through Delta Cargo.

Delta is set to restart service in Argentina, Chile and Ecuador in time for customers seeking warm weather for the holidays, marking Delta’s return to most of the Latin American countries it served prior to the COVID-19 pandemic.

Flights between Atlanta’s Hartsfield International Airport and Santiago’s Arturo Merino International Airport in Chile, and between Atlanta and Quito’s Mariscal Sucre International Airport in Ecuador will resume on Dec. 18, while service from Atlanta to Buenos Aires’ Ezeiza International Airport in Argentina will resume on Dec. 19. The flights to Santiago and Buenos Aires will operate with Boeing 767-400 aircraft and the flights to Quito will operate with Boeing 767-300 aircraft. All three routes will offer Delta One, Delta Comfort+ and Main Cabin service.

With the return of flights to each of the South American countries Delta served prior to the COVID-19 pandemic, Delta is now operating in 35 cities throughout the Caribbean, Mexico, Central and South America.

“We’re ready to welcome our customers back on board and are eager to show them how we’ve transformed the travel experience with enhancements in safety that do not sacrifice comfort or service,” said Delta’s Luciano Macagno, Managing Director – Latin America, the Caribbean and South Florida. “As we restore service to our extensive network, our customers will discover that once they’re ready, they can book their travel with confidence and rest assured that we are putting their safety and that of our employees first.”

For updated information on where Delta is flying, or to learn more about what to expect when traveling with Delta, customers are encouraged to use the airline’s new interactive map that details travel requirement information – including information on travel conditions or restrictions, what to do to prepare, and what to expect upon arrival.

Delta customers throughout Latin America and the Caribbean will benefit from the more than 100 safety and cleanliness initiatives Delta has put in place through its Delta CareStandard, featuring multiple layers of protection from curbside to baggage claim that are meant to ensure safer travel throughout the journey.

Meanwhile, Delta will become the first U.S. airline to partner with the U.S. Centers for Disease Control and Prevention  to keep international customers informed of potential COVID-19 exposure through contact tracing. Under the new voluntary process, customers can directly and securely transmit five requested customer data points to the CDC via U.S. Customs and Border Protection. This will give the CDC access to the data in moments, dramatically decreasing the time it takes to notify affected customers via local health departments.

More Space and Booking Flexibility

As part of its customer-first approach, Delta is the only U.S. airline blocking middle seats and limiting onboard capacity for flights departing now through March 30, 2021. To give customers more choice and control over managing their plans, Delta  announced it is permanently eliminating change fees for international travel originating in North America*, after having already eliminated change fees for travel within the U.S., Puerto Rico and the U.S. Virgin Islands, excluding Basic Economy fares.

Transport of Essential Goods and Services

Throughout the COVID-19 pandemic, Delta Cargo has kept the supply chain flowing. With the return of service to each market, Delta’s flights also offer extensive belly cargo capacity, allowing Delta Cargo customers to transport essential goods, perishables and supplies between Mexico, Central and South America, the Caribbean and the U.S. The team also has capabilities in place to support vaccine shipments at home and around the world and has begun delivering vaccine shipments as part of the global effort to beat the pandemic.

To find out more or to book a shipment, contact the Delta Cargo Pharma Desk at or +1 (800) 352-2746. In addition, our Cargo Charters team can assist via this form or email at Additional information about Delta Cargo can be viewed at  

Delta’s flight schedule remains subject to change due to the evolving nature of COVID-19, customer demand and government travel regulations. For more information on Delta’s response to COVID-19, visit

Delta’s Atlanta-Santiago Schedule**: 





DL 147

ATL: 7:44 p.m.

SCL: 7:00 a.m.+1

Monday, Wednesday, Friday, Sunday

DL 146

SCL: 10:30 p.m.

ATL: 6:06 a.m. +1

Monday, Tuesday, Thursday, Saturday

**First flight from SCL departs Dec. 19. Flights operate daily in January 2021. 

Delta’s Atlanta-Quito Schedule***: 





DL 633

ATL: 6:00 p.m.

UIO: 11:15 p.m.


DL 150

UIO: 1:15 a.m.

ATL: 6:24 a.m.


***First flight from UIO departs Dec. 19. Will not operate Tuesday and Thursday in January 2021 and returns to daily service in February 2021. 

Delta’s Atlanta-Buenos Aires Schedule****: 





DL 101

ATL: 8:23 p.m.

EZE: 8:30 a.m.+1

Tuesday,Thursday, Saturday

DL 150

EZE: 9:15 p.m.

ATL: 5:32 a.m.

Wednesday, Friday, Sunday

****First flight will depart EZE on Dec. 20. 

*No change fees on Delta tickets for travel originating from North America to anywhere in the world (including flights operated by joint venture and codeshare partners). Basic Economy fares are excluded.